Ten countries from the European Research Area are joining this call: Austria, Belgium (Flanders), France, Germany, Israel, The Netherlands, Poland, Portugal, Spain and Turkey.
The aim of this call is provide young, independent investigators the opportuinity of building transnational collaborations in the field of rare disease research.
Transnational research proposals must cover at least one of the following areas, which are equal in relevance for this call:
a/ Collaborative research using patient databases and corresponding collections of biological material that would generally not be possible at a national scale. This research must have clear potential for clinical/public helath or socio-economic application and well-defined scientific objectives e.g.:
- Definition of new nosological entities, epidemiological studies, genotype/phenotype correlations, natural history of diseases
- Characterisation of the genetic/molecular basis of specific diseases
b/ Research on rare diseases including genetic, epigenetic and pathophysiological studies, using innovative and shared resources, technologies (OMICS, new generation sequencing, etc.) and expertise. The clinical relevance of this research must be clearly demonstrated;
c/ Research on development of applications for diagnosis and therapies for rare diseases. This may include identification, characterization and/or validation of (bio)-markers for diagnosis and prognosis, development of innovative screening systems and diagnostic tools, the generation of relevant cellular and/or animal models, and preclinical studies using pharmacological, gene or cell therapies;
d/ Patient oriented research in the area of social and human sciences - e.g. psychological, psychosocial and behavioral research - as well as health services and helath economy research in the field of rare disorders.
Interventional clinical trials are excluded from the scope of the call.
Projects shall involve a group of rare diseases or a single rare disease following the European definition i.e. a disease affecting not more than five in 10 000 persons in the European Community. Rare infectious diseases, rare cancers and rare adverse drug events in treatments of common diseases are excluded from the scope of this call.
Project proposals must clearly demonstrate the potential health impact as well as the added-value of transnational collaboration: gathering a critical mass of patients/biological material, sharing of resources (models, databases, diagnosis etc.), harmonization of data, sharing of specific know-how and/or innovative technologies, etc.
Funding is granted for a maximum of three years.
Who can apply
Applicants must have the necessary qualifications (postdoctoral experience) and the required infrastructure to perform the project. It is essential that applicants have published excellent work in the international scientific journals or have made recognized contributions in the scientific community to the development of a particular field. Candindates must have prove that they are scientifically independent, for example that they lead or have led a research group or project.
Each submitted proposal must involve a minimum of 3 and a maximum of 6 research groups from at least 3 different countries participating to this call: Austria, Belgium, France, Germany, Israel, The Netherlands, Poland, Portugal and Spain.
All prinicipal investigators, including the coordinator of such consortium must be "young investigators" (see below).
The young investigator must have been awarded his/her first PhD/MD or equivalent doctoral degree, at least 2 and up to 10 years prior pre-proposal submission deadline of the E-Rare-2 JTC 2012. Extensions to this period may be allowed in case of eligible career breaks, which must be properly documented. The cumulative eligibility period should not in any case surpass 14 years and 6 months following the award of the first PhD/MD.
No allowance will be made for principal investigators working part-time.
Looking for collaborations?
If you are looking for collaborations we invite you to post your demand on our FORUM
The submission and evaluation process will be managed by the E-Rare-2 secretariat for the Joint Transnational Call 2012 (JTC 2012). Whilst research groups from several countries will submit applications jointly, individual groups will be funded by the individual funding organisation of their country/region that is participating in the E-Rare-2 JTC 2012. Applicants are therefore subject to eligibility criteria of individual funding organisations.
There will be a two-stage submission procedure: joint pre-proposals (in English) must be received by the Joint Call Secretariat in an electronic version no later than 31st January 2012 at 12:00 CET. The pre-proposals that are selected by the international Scientific Evaluation Committee (SEC) will be invited to submit a full proposal. The decision on selection of applicants for invitation to full proposal submission will be communicated by the start of April 2012.
Pre-proposals should be submitted electronically starting from 10 January 2011 on the following website: http://www.pt-it.de/ptoutline/application/erare11
31 January 2012, 12:00 CET - Deadline for submission of pre-proposals (electronic submission only)
24 May 2012, 12:00 CET - Deadline for submission of full proposals (electronic submission only)